Anti-TEA domain family member 2抗体(ab123276)

概述

  • 产品名称Anti-TEA domain family member 2抗体
    参阅全部 TEA domain family member 2 一抗
  • 描述
    兔多克隆抗体to TEA domain family member 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 266-295 of Human TEA domain family member 2 (NP_003589.1).

  • 阳性对照
    • Human placenta tissue lysates; Mouse NIH 3T3 cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab123276 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 49 kDa.

靶标

  • 功能Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
  • 序列相似性Contains 1 TEA DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Embryonic TEA domain containing factor antibody
    • Etdf antibody
    • ETEF 1 antibody
    • ETF antibody
    • TEA domain family member 2 antibody
    • TEAD 2 antibody
    • TEAD-2 antibody
    • TEAD2 antibody
    • Tead2 protein (TEA domain family member 2 (Mapped), isoform CRA_b) antibody
    • TEAD2_HUMAN antibody
    • TEF 4 antibody
    • TEF4 antibody
    • Transcriptional enhancer factor 4 antibody
    • Transcriptional enhancer factor TEF 4 antibody
    • Transcriptional enhancer factor TEF-4 antibody
    see all

Anti-TEA domain family member 2 antibody 图像

  • Anti-TEA domain family member 2 antibody (ab123276) at 1/100 dilution + Human placenta tissue lysates at 35 µg
    Developed using the ECL technique

    Predicted band size : 49 kDa
  • Anti-TEA domain family member 2 antibody (ab123276) at 1/100 dilution + Mouse NIH 3T3 cell line lysates at 35 µg
    Developed using the ECL technique

    Predicted band size : 49 kDa

Anti-TEA domain family member 2 antibody (ab123276)参考文献

ab123276 has not yet been referenced specifically in any publications.

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