Anti-TDO2/TDO抗体(ab76859)
Key features and details
- Mouse polyclonal to TDO2/TDO
- Suitable for: ELISA, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TDO2/TDO抗体
参阅全部 TDO2/TDO 一抗 -
描述
小鼠多克隆抗体to TDO2/TDO -
宿主
Mouse -
经测试应用
适用于: ELISA, WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human TDO2/TDO. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: NP_005642.1 -
阳性对照
- TDO2/TDO transfected lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab76859于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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WB |
1/500 - 1/1000. Predicted molecular weight: 48 kDa.
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说明 |
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ELISA
Use at an assay dependent concentration. |
WB
1/500 - 1/1000. Predicted molecular weight: 48 kDa. |
靶标
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功能
Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin. -
通路
Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2. -
序列相似性
Belongs to the tryptophan 2,3-dioxygenase family. - Information by UniProt
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数据库链接
- Entrez Gene: 6999 Human
- Omim: 191070 Human
- SwissProt: P48775 Human
- Unigene: 183671 Human
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别名
- 3-dioxygenase antibody
- T23O_HUMAN antibody
- TDO 2 antibody
see all
图片
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All lanes : Anti-TDO2/TDO antibody (ab76859) at 1/500 dilution
Lane 1 : TDO2/TDO transfected 293T cells lysate
Lane 2 : Non transfected 293T cells lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 48 kDa
Observed band size: 48 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab76859 被引用在 1 文献中.
- Perez-Pardo P et al. Pharmacological validation of TDO as a target for Parkinson's disease. FEBS J 288:4311-4331 (2021). PubMed: 33471408