概述

  • 产品名称
    TCS JNK 5a
  • 描述
    Selective JNK2/3 inhibitor
  • 生物学描述
    Selective JNK2/3 inhibitor (pIC50 values are <5.6, 6.5 and 6.7 for JNK1, JNK2 and JNK3, respectively). No selectivity for 30 other kinases including p38 (pIC50 = <4.8), ERK2, Alk5, c-Fms, CDK-2, EGFR, ErbB2, GSK3β, PLK1, Src, Tie-2 and VegFr2 (pIC50 = <5).
  • 纯度
    > 99%

性能

文献

This product has been referenced in:
  • Angell RM  et al. N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3. Bioorg Med Chem Lett 17:1296-301 (2007). Read more (PubMed: 17194588) »

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