Anti-TCR alpha + TCR beta抗体[R73] (ab91121)

概述

  • 产品名称Anti-TCR alpha + TCR beta抗体[R73]
    参阅全部 TCR alpha + TCR beta 一抗
  • 描述
    小鼠单克隆抗体[R73] to TCR alpha + TCR beta
  • 经测试应用适用于: WB, IP, Flow Cyt, IHC-Frmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Tissue/ cell preparation - Rat T blasts and Rat erythrocytes.

  • 阳性对照
    • LOU Rat splenocytes

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号R73
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab91121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
Flow Cyt
IHC-Fr
  • 应用说明Flow Cyt: Use 0.25 µg for 106 cells and use a 100 µl total staining volume
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
    • 细胞定位Type I membrane protein.
    • 数据库链接
    • 别名
      • FLJ22602 antibody
      • MGC117436 antibody
      • MGC22624 antibody
      • MGC23964 antibody
      • MGC71411 antibody
      • T cell antigen receptor alpha polypeptide antibody
      • T cell antigen receptor beta polypeptide T cell receptor beta cluster antibody
      • T cell receptor alpha (V D J C) antibody
      • T cell receptor alpha chain C region antibody
      • T cell receptor alpha constant antibody
      • T cell receptor alpha locus antibody
      • T cell receptor beta cluster antibody
      • T cell receptor beta locus antibody
      • TCRA antibody
      • TCRB antibody
      • TCRD antibody
      • TRA antibody
      • TRAC antibody
      • TRB antibody
      see all

    Anti-TCR alpha + TCR beta antibody [R73] 图像

    • Staining of LOU Rat splenocytes with ab91121 at 0.125 µg (blue histogram), or purified Mouse IgG1k, isotype control at 0.5 µg (green histogram), followed by treatment with FITC anti-mouse IgG. Total viable cells were used for analysis.

    Anti-TCR alpha + TCR beta antibody [R73] (ab91121)参考文献

    This product has been referenced in:
    • Hünig T  et al. A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes. J Exp Med 169:73-86 (1989). Read more (PubMed: 2783336) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"