概述

  • 产品名称Anti-Tcl1抗体
    参阅全部 Tcl1 一抗
  • 描述
    山羊多克隆抗体to Tcl1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Macaque Monkey
  • 免疫原

    Synthetic peptide:

    QLYPDGRYRSSD

    , corresponding to internal sequence amino acids 77-88 of Human Tcl1

  • 阳性对照
    • Daudi and Jurkat cells.

性能

应用

Our Abpromise guarantee covers the use of ab65939 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 13 kDa).
    Peptide ELISA: antibody detection limit dilution 1:32,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
    • 组织特异性Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
    • 疾病相关Note=Chromosomal aberrations activating TCL1A are found in chronic T-cell leukemias (T-CLL). Translocation t(14;14)(q11;q32); translocation t(7;14)(q35;q32); inversion inv(14)(q11;q32) that involves the T-cell receptor alpha/delta loci.
    • 序列相似性Belongs to the TCL1 family.
    • 细胞定位Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum. Microsomal fraction.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Anti TCL1A antibody
      • Lymphoma/leukemia, T-cell antibody
      • Oncogene TCL-1 antibody
      • Oncogene TCL1 antibody
      • P14 TCL1 antibody
      • P14 TCL1 protein antibody
      • Protein p14 TCL1 antibody
      • T cell leukemia 1 antibody
      • T cell lymphoma 1 antibody
      • T cell lymphoma 1A antibody
      • T-cell leukemia/lymphoma protein 1A antibody
      • TCL 1 protein antibody
      • TCL1 antibody
      • TCL1 oncogene antibody
      • TCL1 PEN antibody
      • Tcl1a antibody
      • TCL1A antibody antibody
      • TCL1A_HUMAN antibody
      see all

    Anti-Tcl1 antibody 图像

    Anti-Tcl1 antibody (ab65939)参考文献

    ab65939 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"