概述

  • 产品名称Anti-TCEB2抗体
    参阅全部 TCEB2 一抗
  • 描述
    兔多克隆抗体to TCEB2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 20-48 of Human TCEB2 (NP_009039.1).

  • 阳性对照
    • K-562 cell line lysates

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab123402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 13 kDa.

靶标

  • 功能SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
    The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 ubiquitin-like domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EloB antibody
    • ELOB_HUMAN antibody
    • Elongin 18 kDa subunit antibody
    • Elongin B antibody
    • Elongin-B antibody
    • RNA polymerase II transcription factor SIII p18 subunit antibody
    • RNA polymerase II transcription factor SIII subunit B antibody
    • SIII antibody
    • SIII p18 antibody
    • TCEB 2 antibody
    • Tceb2 antibody
    • Transcription elongation factor B (SIII) polypeptide 2 antibody
    • Transcription elongation factor B polypeptide 2 antibody
    see all

Anti-TCEB2 antibody 图像

  • Anti-TCEB2 antibody (ab123402) at 1/100 dilution + K-562 cell line lysates at 35 µg

    Predicted band size : 13 kDa

Anti-TCEB2 antibody (ab123402)参考文献

ab123402 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123402.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"