概述

  • 产品名称
  • 描述
    兔多克隆抗体to Tbx4
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Sheep, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide derived from residues 257 - 306 of human Tbx4.

  • 阳性对照
    • HepG2 cell lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab28634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 60 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
  • 疾病相关
    Defects in TBX4 are the cause of small patella syndrome (SPS) [MIM:147891]; also known as ischiopatellar dysplasia or Scott-Taor syndrome. SPS is an autosomal dominant skeletal dysplasia characterized by patellar aplasia or hypoplasia and by anomalies of the pelvis and feet, including disrupted ossification of the ischia and inferior pubic rami.
  • 序列相似性
    Contains 1 T-box DNA-binding domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • SPS antibody
    • T box 4 antibody
    • T box protein 4 antibody
    • T box transcription factor TBX 4 antibody
    • T box transcription factor TBX4 antibody
    • T-box protein 4 antibody
    • T-box transcription factor TBX4 antibody
    • TBX 4 antibody
    • TBX4 antibody
    • TBX4_HUMAN antibody
    see all

Anti-Tbx4 antibody 图像

  • Anti-Tbx4 antibody (ab28634) at 0.5 µg/ml + HepG2 cell lysate 10ug.

    Secondary
    HRP conjugated anti-Rabbit IgG at 1: 50,000 - 100,000

    Predicted band size : 60 kDa
    Observed band size : 59 kDa (why is the actual band size different from the predicted?)

实验方案

Anti-Tbx4 antibody (ab28634)参考文献

This product has been referenced in:
  • Osz K  et al. The thrombospondin-1 receptor CD36 is an important mediator of ovarian angiogenesis and folliculogenesis. Reprod Biol Endocrinol 12:21 (2014). IHC . Read more (PubMed: 24628875) »

See 1 Publication for this product

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