概述

  • 产品名称Anti-Tbx3抗体
    参阅全部 Tbx3 一抗
  • 描述
    小鼠单克隆抗体to Tbx3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: KENGTSDESS SEQAAFNCFA QASSPAASTV GTSNLKDLCP SEGESDAEAE SKEEHGPEAC DAAKISTTTS EEPCRDKGSP AVKAHLFAAE RPRDSGRLDK , corresponding to amino acids 311-411 of Human Tbx3

性能

应用

Our Abpromise guarantee covers the use of ab58264 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 79 kDa.

靶标

  • 功能Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.
  • 组织特异性Widely expressed.
  • 疾病相关Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.
  • 序列相似性Contains 1 T-box DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Bladder cancer related protein XHL antibody
    • T box 3 antibody
    • T-box protein 3 antibody
    • T-box transcription factor TBX3 antibody
    • Tbx3 antibody
    • TBX3 ISO antibody
    • TBX3_HUMAN antibody
    • UMS antibody
    • XHL antibody
    see all

Anti-Tbx3 antibody 图像



  • Predicted band size : 79 kDa
    Tbx3 antibody (ab58264) at 1ug/lane + IMR-32 cell lysate at 25ug/lane.
  • Ab58264 (10 ug/ml) staining of TBX3 in HeLa cells by immunofluorescence.

Anti-Tbx3 antibody (ab58264)参考文献

This product has been referenced in:
  • Krstic M  et al. The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer. BMC Cancer 16:671 (2016). WB ; Human . Read more (PubMed: 27553211) »
  • Fillmore CM  et al. Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. Proc Natl Acad Sci U S A : (2010). WB ; Human . Read more (PubMed: 21098263) »

See all 2 Publications for this product

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