Anti-TBX1抗体[EPR3289(2)] (ab109313)


  • 产品名称Anti-TBX1抗体[EPR3289(2)]
    参阅全部 TBX1 一抗
  • 描述
    兔单克隆抗体[EPR3289(2)] to TBX1
  • 经测试应用适用于: WB, IPmore details
    不适用于: Flow Cyt,ICC or IHC-P
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

  • 阳性对照
    • PC12, F9, Neuro-2a, Jurkat and NCCIT cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.



Our Abpromise guarantee covers the use of ab109313 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).
IP 1/10 - 1/100.
  • 应用说明Is unsuitable for Flow Cyt,ICC or IHC-P.
  • 靶标

    • 功能Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries.
    • 疾病相关Haploinsufficiency of the TBX1 gene is responsible for most of the physical malformations present in DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS) [MIM:188400, 192430]. DGS is characterized by the association of several malformations: hypoplastic thymus and parathyroid glands, congenital conotruncal cardiopathy, and a subtle but characteristic facial dysmorphology. VCFS is marked by the association of congenital conotruncal heart defects, cleft palate or velar insufficiency, facial dysmorpholgy and learning difficulties. It is now accepted that these two syndromes represent two forms of clinical expression of the same entity manifesting at different stages of life.
      Defects in TBX1 are a cause of DiGeorge syndrome (DGS) [MIM:188400].
      Defects in TBX1 are a cause of velocardiofacial syndrome (VCFS) [MIM:192430].
      Defects in TBX1 are a cause of conotruncal heart malformations (CTHM) [MIM:217095]. CTHM consist of cardiac outflow tract defects, such as tetralogy of Fallot, pulmonary atresia, double-outlet right ventricle, truncus arteriosus communis, and aortic arch anomalies.
    • 序列相似性Contains 1 T-box DNA-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Brachyury antibody
      • CAFS antibody
      • CTHM antibody
      • DGCR antibody
      • DGS antibody
      • DORV antibody
      • T box antibody
      • T box 1 antibody
      • T box 1 transcription factor antibody
      • T box 1 transcription factor C antibody
      • T box protein 1 antibody
      • T box transcription factor TBX 1 antibody
      • T box transcription factor TBX1 antibody
      • T-box protein 1 antibody
      • T-box transcription factor TBX1 antibody
      • TBX 1 antibody
      • TBX 1C antibody
      • tbx1 antibody
      • TBX1_HUMAN antibody
      • TBX1C antibody
      • Testis specific T box protein antibody
      • Testis-specific T-box protein antibody
      • TGA antibody
      • VCFS antibody
      see all

    Anti-TBX1 antibody [EPR3289(2)] 图像

    • All lanes : Anti-TBX1 antibody [EPR3289(2)] (ab109313) at 1/1000 dilution

      Lane 1 : PC12 lysate
      Lane 2 : F9 lysate
      Lane 3 : Neuro-2a lysate
      Lane 4 : Jurkat lysate
      Lane 5 : NCCIT lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 43 kDa
      Observed band size : 43 kDa

    Anti-TBX1 antibody [EPR3289(2)] (ab109313)参考文献

    ab109313 has not yet been referenced specifically in any publications.

    Product Wall

    This antibody recognizes an epitope within AA 90-120.

    Thank you for contacting me and for keeping me updated about the results with the Tbx1 and Twist antibodies. I'm sorry to hear that the results are not good at this point, but please let me know if there is anything I can do to help in that situation. ...

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    Thank you for your call today. Please see below for your testing codes, and let me know if you have any questions or need anything else from me.

    Ab109313: ***
    Ab49254: ***

    Expiration date: August 28, 2012. <...

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