Anti-TBX1抗体- Carboxyterminal end (ab65935)

概述

  • 产品名称Anti-TBX1抗体- Carboxyterminal end
    参阅全部 TBX1 一抗
  • 描述
    兔多克隆抗体to TBX1 - Carboxyterminal end
  • 特异性Detects endogenous levels of total TBX1 protein.
  • 经测试应用适用于: ELISA, ICC/IF, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from C-terminal of human TBX1.

  • 阳性对照
    • A549 cells, extracts from COLO205 cells

性能

应用

Our Abpromise guarantee covers the use of ab65935 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
ICC/IF
WB
  • 应用说明ELISA: 1/20000.
    ICC/IF: 1/500 - 1/1000.
    WB: 1/500 - 1/1000. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries.
    • 疾病相关Haploinsufficiency of the TBX1 gene is responsible for most of the physical malformations present in DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS) [MIM:188400, 192430]. DGS is characterized by the association of several malformations: hypoplastic thymus and parathyroid glands, congenital conotruncal cardiopathy, and a subtle but characteristic facial dysmorphology. VCFS is marked by the association of congenital conotruncal heart defects, cleft palate or velar insufficiency, facial dysmorpholgy and learning difficulties. It is now accepted that these two syndromes represent two forms of clinical expression of the same entity manifesting at different stages of life.
      Defects in TBX1 are a cause of DiGeorge syndrome (DGS) [MIM:188400].
      Defects in TBX1 are a cause of velocardiofacial syndrome (VCFS) [MIM:192430].
      Defects in TBX1 are a cause of conotruncal heart malformations (CTHM) [MIM:217095]. CTHM consist of cardiac outflow tract defects, such as tetralogy of Fallot, pulmonary atresia, double-outlet right ventricle, truncus arteriosus communis, and aortic arch anomalies.
    • 序列相似性Contains 1 T-box DNA-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Brachyury antibody
      • CAFS antibody
      • CTHM antibody
      • DGCR antibody
      • DGS antibody
      • DORV antibody
      • T box antibody
      • T box 1 antibody
      • T box 1 transcription factor antibody
      • T box 1 transcription factor C antibody
      • T box protein 1 antibody
      • T box transcription factor TBX 1 antibody
      • T box transcription factor TBX1 antibody
      • T-box protein 1 antibody
      • T-box transcription factor TBX1 antibody
      • TBX 1 antibody
      • TBX 1C antibody
      • tbx1 antibody
      • TBX1_HUMAN antibody
      • TBX1C antibody
      • Testis specific T box protein antibody
      • Testis-specific T-box protein antibody
      • TGA antibody
      • VCFS antibody
      see all

    Anti-TBX1 antibody - Carboxyterminal end 图像

    • All lanes : Anti-TBX1 antibody - Carboxyterminal end (ab65935) at 1/500 dilution

      Lane 1 : extracts from COLO205 cells
      Lane 2 : extracts from COLO205 cells with immunizing peptide at 10 µg

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 44 kDa
      Observed band size : 44 kDa
    • ab65935 at 1/500 dilution staining A549 cells without (left) and with (right) immunizing peptide.

    Anti-TBX1 antibody - Carboxyterminal end (ab65935)参考文献

    ab65935 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab65935.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"