• 产品名称Anti-TBX1抗体
    参阅全部 TBX1 一抗
  • 描述
    兔多克隆抗体to TBX1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Rabbit, Guinea pig, Cat
  • 免疫原

    Synthetic peptide within residues: PVASPTQPSG TEKGGHVLKD KEVKAETSRN TPEREVELLR DAGGCVNLGL, corresponding to internal sequence amino acids 324-373 of Human TBX1 (NP_542377)

  • 阳性对照
    • Human fetal lung lysate.



Our Abpromise guarantee covers the use of ab84730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • 功能Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries.
  • 疾病相关Haploinsufficiency of the TBX1 gene is responsible for most of the physical malformations present in DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS) [MIM:188400, 192430]. DGS is characterized by the association of several malformations: hypoplastic thymus and parathyroid glands, congenital conotruncal cardiopathy, and a subtle but characteristic facial dysmorphology. VCFS is marked by the association of congenital conotruncal heart defects, cleft palate or velar insufficiency, facial dysmorpholgy and learning difficulties. It is now accepted that these two syndromes represent two forms of clinical expression of the same entity manifesting at different stages of life.
    Defects in TBX1 are a cause of DiGeorge syndrome (DGS) [MIM:188400].
    Defects in TBX1 are a cause of velocardiofacial syndrome (VCFS) [MIM:192430].
    Defects in TBX1 are a cause of conotruncal heart malformations (CTHM) [MIM:217095]. CTHM consist of cardiac outflow tract defects, such as tetralogy of Fallot, pulmonary atresia, double-outlet right ventricle, truncus arteriosus communis, and aortic arch anomalies.
  • 序列相似性Contains 1 T-box DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Brachyury antibody
    • CAFS antibody
    • CTHM antibody
    • DGCR antibody
    • DGS antibody
    • DORV antibody
    • T box antibody
    • T box 1 antibody
    • T box 1 transcription factor antibody
    • T box 1 transcription factor C antibody
    • T box protein 1 antibody
    • T box transcription factor TBX 1 antibody
    • T box transcription factor TBX1 antibody
    • T-box protein 1 antibody
    • T-box transcription factor TBX1 antibody
    • TBX 1 antibody
    • TBX 1C antibody
    • tbx1 antibody
    • TBX1_HUMAN antibody
    • TBX1C antibody
    • Testis specific T box protein antibody
    • Testis-specific T-box protein antibody
    • TGA antibody
    • VCFS antibody
    see all

Anti-TBX1 antibody 图像

  • Anti-TBX1 antibody (ab84730) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal lung lysate at 10 µg

    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 43 kDa
    Observed band size : 43 kDa

Anti-TBX1 antibody (ab84730)参考文献

ab84730 has not yet been referenced specifically in any publications.

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Thank you for your patience in this matter. I have talked to the lab and we are able to provide more of lot#906622, although the lot number will be different on the vial you receive, it will be the same product. The reason for this is that we c...

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Thank you for contacting Abcam. I am in contact with the lab about whether we have more of ab84730, lot#906622 in the freezers, as we are showing that we do not have any ab84730 in stock. I will let you know as soon as I hear anything.