Anti-TBRG1抗体- Aminoterminal end (ab71318)

概述

  • 产品名称
    Anti-TBRG1抗体- Aminoterminal end
    参阅全部 TBRG1 一抗
  • 描述
    兔多克隆抗体to TBRG1 - Aminoterminal end
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide selected from the N terminal region of human TBRG1 conjugated to KLH

  • 阳性对照
    • Mouse kidney tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab71318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).

靶标

  • 相关性
    Function: Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. Tissue specificity: Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell lymphoma. Similarity: Belongs to the TBRG1 family. Contains 1 FYR C-terminal domain. Contains 1 FYR N-terminal domain. PTM: Ubiquitinated; mediated by MDM2 and leading to its subsequent proteasomal degradation.
  • 细胞定位
    Nuclear
  • 数据库链接
  • 别名
    • NIAM antibody
    • Nuclear interactor of ARF and Mdm2 antibody
    • TB 5 antibody
    • tbrg1 antibody
    • TBRG1 regulator 1 antibody
    • TBRG1_HUMAN antibody
    • Transforming growth factor beta regulator 1 antibody
    see all

图片

  • Anti-TBRG1 antibody - Aminoterminal end (ab71318) at 1/60 dilution + mouse kidney tissue lysates at 35 µg

    Predicted band size : 45 kDa
    Observed band size : 45 kDa

实验方案

文献

ab71318 has not yet been referenced specifically in any publications.

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