概述

  • 产品名称
  • 描述
    兔多克隆抗体to TBCE
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide, corresponding to a region between amino acids 371-400 from the central region of Human TBCE (NP_003184).

  • 阳性对照
    • K562 cell line lysates

性能

应用

Our Abpromise guarantee covers the use of ab103006 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 59 kDa.

靶标

  • 功能
    Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation.
  • 疾病相关
    Defects in TBCE are a cause of hypoparathyroidism-retardation-dysmorphism syndrome (HRD) [MIM:241410]; also known as hypoparathyroidism with short stature, mental retardation, and seizures or Sanjad-Sakati syndrome. HRD is an autosomal recessive disorder reported almost exclusively in Middle Eastern populations.
    Defects in TBCE are the cause of Kenny-Caffey syndrome type 1 (KCS1) [MIM:244460]. KCS1 is similar to HRD with the additional features of osteosclerosis and recurrent bacterial infections.
  • 序列相似性
    Belongs to the TBCE family.
    Contains 1 CAP-Gly domain.
    Contains 7 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
  • 细胞定位
    Cytoplasm. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HRD antibody
    • KCS antibody
    • KCS1 antibody
    • Pac2 antibody
    • tbce antibody
    • TBCE_HUMAN antibody
    • Tubulin specific chaperone e antibody
    • Tubulin-folding cofactor E antibody
    • Tubulin-specific chaperone E antibody
    see all

图片

  • Anti-TBCE antibody (ab103006) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size : 59 kDa

实验方案

文献

ab103006 has not yet been referenced specifically in any publications.

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