Anti-Tau tubulin kinase 2抗体(ab116096)

概述

  • 产品名称Anti-Tau tubulin kinase 2抗体
    参阅全部 Tau tubulin kinase 2 一抗
  • 描述
    兔多克隆抗体to Tau tubulin kinase 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human, Pig
  • 免疫原

    Synthetic peptide corresponding to Mouse Tau tubulin kinase 2 aa 270-319 (N terminal).
    Sequence:

    KPDYQLLTSVFDNSIKTFGVIESDPFDWEKSGTDGSLTTTTTSATPQLHT


    Database link: Q3UVR3

  • 阳性对照
    • Mouse thymus lysate.

性能

应用

Our Abpromise guarantee covers the use of ab116096 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 137 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Serine/threonine kinase which is able to phosphorylate tau on serines.
  • 疾病相关Defects in TTBK2 are the cause of spinocerebellar ataxia type 11 (SCA11) [MIM:604432]. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA11 is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder.
  • 序列相似性Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA0847 antibody
    • mKIAA0847 antibody
    • SCA11 antibody
    • Spinocerebellar ataxia 11 antibody
    • Tau tubulin kinase 2 antibody
    • Tau-tubulin kinase 2 antibody
    • TTBK antibody
    • TTBK 2 antibody
    • TTBK1 antibody
    • TTBK2 antibody
    • TTBK2_HUMAN antibody
    • TTK antibody
    see all

Anti-Tau tubulin kinase 2 antibody 图像

  • Anti-Tau tubulin kinase 2 antibody (ab116096) at 1 µg/ml + Mouse thymus lysate at 10 µg

    Predicted band size : 137 kDa

Anti-Tau tubulin kinase 2 antibody (ab116096)参考文献

ab116096 has not yet been referenced specifically in any publications.

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