概述

  • 产品名称Anti-TARC抗体
    参阅全部 TARC 一抗
  • 描述
    兔多克隆抗体to TARC
  • 经测试应用适用于: WB, Neutralising, Indirect ELISA, Sandwich ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>98%) recombinant Human TARC

性能

  • 形式Lyophilised:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab109836 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa. The detection limit for recombinant Human TARC is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Neutralising Use a concentration of 2 - 3 µg/ml. to yield one-half maximal inhibition [ND50] of the biological activity of Human TARC (100 ng/ml)
Indirect ELISA Use a concentration of 0.5 - 2 µg/ml. ab109836 in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human TARC (using 100 µl/well antibody solution).
Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to TARC (Biotin) (ab84279). ab109836 in conjunction with ab84279 as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human TARC (using 100 µl/well antibody solution).

靶标

  • 功能Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
  • 组织特异性Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.
  • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A-152E5.3 antibody
    • A152E53 antibody
    • ABCD 2 antibody
    • ABCD2 antibody
    • C-C motif chemokine 17 antibody
    • CC chemokine TARC antibody
    • CCL17 antibody
    • CCL17_HUMAN antibody
    • Chemokine CC Motif Ligand 17 antibody
    • MGC138271 antibody
    • MGC138273 antibody
    • SCYA17 antibody
    • Small Inducible Cytokine A17 antibody
    • Small Inducible Cytokine A17 Precursor antibody
    • Small Inducible Cytokine Subfamily A (Cys Cys) antibody
    • Small Inducible Cytokine Subfamily A (Cys Cys) Member 17 antibody
    • Small-inducible cytokine A17 antibody
    • T Cell Directed CC Chemokine antibody
    • Thymus and activation regulated chemokine antibody
    • Thymus and activation-regulated chemokine antibody
    see all

Anti-TARC antibody (ab109836)参考文献

This product has been referenced in:
  • la Sala A  et al. Dendritic cells exposed to extracellular adenosine triphosphate acquire the migratory properties of mature cells and show a reduced capacity to attract type 1 T lymphocytes. Blood 99:1715-22 (2002). Read more (PubMed: 11861288) »

See 1 Publication for this product

Product Wall

Thanks for your inquiry. Based upon sequence homology, I would not expect any of the antibodies to cross react with mouse as there is only a 64% homology. Please let me know if you require further assistance.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"