概述

  • 产品名称Anti-TARBP1抗体
    参阅全部 TARBP1 一抗
  • 描述
    兔多克隆抗体to TARBP1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    A 17 amino acids synthetic peptide conjugated to KLH, corresponding to a region near the center of Human TARBP1.

  • 阳性对照
    • Human prostate and Human adrenal tissue

性能

应用

Our Abpromise guarantee covers the use of ab115896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 182 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA.
  • 序列相似性Belongs to the RNA methyltransferase TrmH family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ30482 antibody
    • Probable methyltransferase TARBP1 antibody
    • TAR (HIV) RNA binding protein 1 antibody
    • TAR antibody
    • TAR RNA loop binding protein antibody
    • TAR RNA-binding protein 1 antibody
    • TAR RNA-binding protein of 185 kDa antibody
    • TARB1_HUMAN antibody
    • TARBP1 antibody
    • TRM3 antibody
    • TRP-185 antibody
    • TRP185 antibody
    see all

Anti-TARBP1 antibody 图像

  • ab115896, at 5 ug/ml, staining TARBP1 in formalin fixed, paraffin embedded Human Prostate by Immunohistochemistry. Developed using biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • ab115896, at 5 ug/ml, staining TARBP1 in formalin fixed, paraffin embedded Human adrenal by Immunohistochemistry. Developed using biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-TARBP1 antibody (ab115896)参考文献

ab115896 has not yet been referenced specifically in any publications.

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