概述

  • 产品名称Anti-Tapasin抗体
    参阅全部 Tapasin 一抗
  • 描述
    兔多克隆抗体to Tapasin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Sheep, Horse, Pig, African Green Monkey
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 359-408 (SVSLSGHLQP PPVTTEQHGA RYACRIHHPS LPASGRSAEV TLEVAGLSGP) of Human Tapasin (NP_003181).

  • 阳性对照
    • OVCAR-3 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab104806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
  • 组织特异性Neutrophils, mostly in fully differentiated cells.
  • 序列相似性Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • 结构域The N-terminus is required for efficient association with MHC class I molecule and for a stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminus region.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • NGS 17 antibody
    • NGS-17 antibody
    • NGS17 antibody
    • TAP associated protein antibody
    • TAP binding protein antibody
    • TAP binding protein (tapasin) antibody
    • TAP BP antibody
    • TAP-associated protein antibody
    • TAP-binding protein antibody
    • TAPA antibody
    • Tapasin antibody
    • TAPBP antibody
    • TPN antibody
    • TPSN antibody
    • TPSN_HUMAN antibody
    see all

Anti-Tapasin antibody 图像

  • Anti-Tapasin antibody (ab104806) at 1 µg/ml + OVCAR-3 cell lysate at 10 µg

    Predicted band size : 48 kDa

Anti-Tapasin antibody (ab104806)参考文献

ab104806 has not yet been referenced specifically in any publications.

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