概述

  • 产品名称Anti-TAOK3抗体
    参阅全部 TAOK3 一抗
  • 描述
    兔多克隆抗体to TAOK3
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human TAOK3 (C terminal) conjugated to keyhole limpet haemocyanin.
    Database link: Q9H2K8

  • 阳性对照
    • 293 cell lysates transiently transfected with the JIK gene (WB) Human hepatocarcinoma tissue (IHC)

性能

应用

Our Abpromise guarantee covers the use of ab62915 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 105 kDa (predicted molecular weight: 105 kDa).
ELISA 1/1000.
IHC-P 1/10 - 1/50.

靶标

  • 功能Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.
  • 组织特异性Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm. Cell membrane. Also localized to the peripheral cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CTCL tumor antigen HD CL 09 antibody
    • CTCL-associated antigen HD-CL-09 antibody
    • Cutaneous T cell lymphoma tumor antigen HD CL 09 antibody
    • Cutaneous T-cell lymphoma-associated antigen HD-CL-09 antibody
    • Dendritic cell derived protein kinase antibody
    • Dendritic cell-derived protein kinase antibody
    • DKFZp666H245 antibody
    • DPK antibody
    • FLJ31808 antibody
    • hKFC A antibody
    • hKFC-A antibody
    • JIK antibody
    • JNK/SAPK inhibitory kinase antibody
    • JNK/SAPK-inhibitory kinase antibody
    • Jun kinase inhibitory kinase antibody
    • Jun kinase-inhibitory kinase antibody
    • KDS antibody
    • Kinase from chicken homolog A antibody
    • MAP3K18 antibody
    • Serine kinase antibody
    • Serine/threonine-protein kinase TAO3 antibody
    • STE20 like kinase antibody
    • TAO kinase 3 antibody
    • TAOK3 antibody
    • TAOK3_HUMAN antibody
    • Thousand and one amino acid protein 3 antibody
    see all

Anti-TAOK3 antibody 图像

  • All lanes : Anti-TAOK3 antibody (ab62915) at 1/50 dilution

    Lane 1 : 293 cell lysates nontransfected
    Lane 2 : 293 cell lysates transiently transfected with the JIK gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 105 kDa
    Observed band size : 105 kDa
    Additional bands at : 60 kDa,70 kDa. We are unsure as to the identity of these extra bands.
  • ab62915, at 1/10 dilution, staining TAOK3 in formalin-fixed, paraffin-embedded human hepatocarcinoma tissue by immunohistochemistry. ab62915 was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Anti-TAOK3 antibody (ab62915)参考文献

ab62915 has not yet been referenced specifically in any publications.

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