概述

  • 产品名称
  • 描述
    山羊多克隆抗体to TAOK3
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide corresponding to Human TAOK3 aa 396-411.
    Sequence:

    HKKDHVFIRDEAGHGD


    Database link: Q9H2K8

  • 阳性对照
    • Human Liver lysate

性能

应用

Our Abpromise guarantee covers the use of ab21205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/32000.
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 105 kDa).

靶标

  • 功能
    Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.
  • 组织特异性
    Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
  • 序列相似性
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰
    Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Cytoplasm. Cell membrane. Also localized to the peripheral cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CTCL tumor antigen HD CL 09 antibody
    • CTCL-associated antigen HD-CL-09 antibody
    • Cutaneous T cell lymphoma tumor antigen HD CL 09 antibody
    • Cutaneous T-cell lymphoma-associated antigen HD-CL-09 antibody
    • Dendritic cell derived protein kinase antibody
    • Dendritic cell-derived protein kinase antibody
    • DKFZp666H245 antibody
    • DPK antibody
    • FLJ31808 antibody
    • hKFC A antibody
    • hKFC-A antibody
    • JIK antibody
    • JNK/SAPK inhibitory kinase antibody
    • JNK/SAPK-inhibitory kinase antibody
    • Jun kinase inhibitory kinase antibody
    • Jun kinase-inhibitory kinase antibody
    • KDS antibody
    • Kinase from chicken homolog A antibody
    • MAP3K18 antibody
    • Serine kinase antibody
    • Serine/threonine-protein kinase TAO3 antibody
    • STE20 like kinase antibody
    • TAO kinase 3 antibody
    • TAOK3 antibody
    • TAOK3_HUMAN antibody
    • Thousand and one amino acid protein 3 antibody
    see all

Anti-TAOK3 antibody 图像



  • Predicted band size : 105 kDa

    ab21205 (0.1ug/ml) western blot detection of JIK from human liver lysate.

    ab21205 (0.1ug/ml) western blot detection of JIK from human liver lysate.

实验方案

Anti-TAOK3 antibody (ab21205)参考文献

This product has been referenced in:
  • Kapfhamer D  et al. JNK pathway activation is controlled by Tao/TAOK3 to modulate ethanol sensitivity. PLoS One 7:e50594 (2012). WB ; Mouse . Read more (PubMed: 23227189) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab21205.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册