Tamsulosin hydrochloride (ab120772)

概述

  • 产品名称Tamsulosin hydrochloride
  • 描述
    Potent, selective α1A antagonist
  • 生物学描述Potent and selective α1A antagonist (pKi values are 9.97, 8.86 and 9.64 at α1A, α1B and α1D, respectively). Decreases urethral pressure in vivo with a minimal effect on mean arterial blood pressure.
  • 纯度> 99%

性能

  • 化学名称5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-benzenesulfonamide hydrochloride
  • 分子量444.97
  • 化学结构Chemical Structure
  • 分子式C20H28N2O5S.HCl
  • CAS编号106463-17-6
  • 存放说明Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • 溶解度概述Soluble in DMSO to 100 mM and in water to 10 mM
  • 处理

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • 来源

    Synthetic

  • 研究领域

    Tamsulosin hydrochloride (ab120772)参考文献

    This product has been referenced in:
    • Ohtake A  et al. Effects of tamsulosin on resting urethral pressure and arterial blood pressure in anaesthetized female dogs. J Pharm Pharmacol 58:345-50 (2006). Read more (PubMed: 16536901) »
    • Taguchi K  et al. Effects of tamsulosin metabolites at alpha-1 adrenoceptor subtypes. J Pharmacol Exp Ther 280:1-5 (1997). Read more (PubMed: 8996174) »
    • Takenaka T  et al. [Discovery and development of tamsulosin hydrochloride, a new alpha 1-adrenoceptor antagonist]. Yakugaku Zasshi 115:773-89 (1995). Read more (PubMed: 8531059) »

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