概述

  • 产品名称Anti-Talin 2抗体[68E7]
    参阅全部 Talin 2 一抗
  • 描述
    小鼠单克隆抗体[68E7] to Talin 2
  • 经测试应用适用于: IHC-Fr, ICC/IF, IP, WB, ELISAmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Recombinant fragment, corresponding to amino acids 489-911 of Mouse Talin 2.

  • 阳性对照
    • Fibroblasts
  • 常规说明Growth Conditions: RPMI1650 + Glu + Pen + Strep + 10% FCS @ 37°C + 5%CO2

性能

应用

Our Abpromise guarantee covers the use of ab105458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
ICC/IF 1/100 - 1/1000.
IP 1/100 - 1/1000.
WB 1/100 - 1/1000. Predicted molecular weight: 272 kDa.
ELISA 1/100 - 1/1000.

靶标

  • 功能As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity.
  • 序列相似性Contains 1 FERM domain.
    Contains 1 I/LWEQ domain.
  • 细胞定位Cell junction > focal adhesion. Cell junction > synapse. Cell membrane. Cytoplasm > cytoskeleton. Focal adhesion plaques and synapses.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp451B1011 antibody
    • DKFZp686I0976 antibody
    • DKFZp686K0979 antibody
    • ILWEQ antibody
    • KIAA0320 antibody
    • Talin-2 antibody
    • talin2 antibody
    • TLN 2 antibody
    • TLN2 antibody
    • TLN2_HUMAN antibody
    see all

Anti-Talin 2 antibody [68E7] (ab105458)参考文献

This product has been referenced in:
  • Debrand E  et al. Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms. FEBS J 276:1610-28 (2009). Read more (PubMed: 19220457) »

See 1 Publication for this product

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