Anti-Talin 1抗体[1A11] (ab110080)

概述

  • 产品名称
    Anti-Talin 1抗体[1A11]
    参阅全部 Talin 1 一抗
  • 描述
    小鼠单克隆抗体[1A11] to Talin 1
  • 经测试应用
    适用于: Sandwich ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1052-1150 of Human Talin 1 with proprietary tag (NP_006280).

  • 阳性对照
    • Human Spleen and Testis tissue; PC-12 and Raw 264.7 cell lysates
  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    单克隆
  • 克隆编号
    1A11
  • 同种型
    IgG3
  • 轻链类型
    kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab110080 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Sandwich ELISA Use at an assay dependent dilution. Detection limit for recombinant tagged TLN1 is approximately 0.3 ng/ml as a capture antibody.
WB Use at an assay dependent dilution. Predicted molecular weight: 269 kDa.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能
    Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
  • 序列相似性
    Contains 1 FERM domain.
    Contains 1 I/LWEQ domain.
  • 细胞定位
    Cell projection, ruffle membrane. Cytoplasm, cytoskeleton. Cell surface. Cell junction, focal adhesion. Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).
  • Information by UniProt
  • 数据库链接
  • 别名
    • ILWEQ antibody
    • Talin 1 antibody
    • Talin antibody
    • Talin-1 antibody
    • TLN 1 antibody
    • TLN antibody
    • Tln1 antibody
    • TLN1_HUMAN antibody
    see all

图片

  • ab110080, at 5µg/ml, staining Talin 1 in formalin-fixed, paraffin-embedded Human Spleen tissue by Immunohistochemistry.
  • ab110080, at 5µg/ml, staining Talin 1 in formalin-fixed, paraffin-embedded Human Testis tissue by Immunohistochemistry.
  • Anti-Talin 1 antibody [1A11] (ab110080) + PC-12 cell lysate

    Predicted band size : 269 kDa
  • Anti-Talin 1 antibody [1A11] (ab110080) + Raw 264.7 cell lysate

    Predicted band size : 269 kDa
  • Detection limit for recombinant tagged Talin 1 is approximately 0.3 ng/ml as a capture antibody.

文献

ab110080 has not yet been referenced specifically in any publications.

客户评价及客户问答

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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