产品名称 Anti-Tal1抗体 参阅全部 Tal1 一抗
WB, ELISA more details
Synthetic peptide (Human) corresponding to amino acid residues surrounding T90, conjugated to KLH.
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液 Preservative: 0.09% Sodium Azide
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纯度 Immunogen affinity purified
纯化说明 This antibody is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100. Predicted molecular weight: 34 kDa.
功能 Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.
组织特异性 Leukemic stem cell.
疾病相关 Note=A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL). Translocation t(1;14)(p32;q11) with T-cell receptor alpha chain (TCRA) genes.
序列相似性 Contains 1 basic helix-loop-helix (bHLH) domain.
结构域 The helix-loop-helix domain is necessary and sufficient for the interaction with DRG1.
翻译后修饰 Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia. Ubiquitinated; subsequent to hypoxia-dependent phosphorylation of Ser-122, ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells, since it could not be observed in large vessel endothelial cells.
Information by UniProt
Class A basic helix-loop-helix protein 17 antibody
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"