概述

  • 产品名称Anti-TAG72抗体[B72.3]
    参阅全部 TAG72 一抗
  • 描述
    小鼠单克隆抗体[B72.3] to TAG72
  • 特异性This antibody recognises an oncofetal antigen of >1,000kDa, identified as a Tumor-Associated Glycoprotein (TAG-72) with the properties of a mucin. Weak or no reactivity has been observed with most cell types of normal adult tissue excepting the secretory endometrium.
  • 经测试应用适用于: IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Rat, Hamster, Human
  • 免疫原

    Membrane-enriched fraction of a human breast carcinoma liver metastasis

  • 阳性对照
    • Lung carcinoma or breast cancer.

性能

应用

Our Abpromise guarantee covers the use of ab691 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. Incubation for 30-60 minutes at room temperature is recommended.
IHC-Fr Use at an assay dependent concentration.

靶标

  • 相关性The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
  • 细胞定位Cytoplasmic
  • 别名
    • CA 72.4 antibody
    • TAG 72 antibody
    • Tumor associated glycoprotein 72 antibody

Anti-TAG72 antibody [B72.3] (ab691)参考文献

This product has been referenced in:
  • van Niekerk CC  et al. Differentiation margins of ovarian tumor pathology: first incidences of epithelial ovarian tumors monitored by marker antibodies. Cancer Detect Prev 21:247-57 (1997). Read more (PubMed: 9167042) »
  • Guadagni F  et al. TAG-72 expression and its role in the biological evaluation of human colorectal cancer. Anticancer Res 16:2141-8 (1996). Read more (PubMed: 8694534) »

See all 11 Publications for this product

Product Wall

Thank you for your phone call this week and for your patience while I looked into your questions. I have heard back from the production lab of ab691, and the IgG concentrations vary among the lots that we have in stock: 60ug/mL for lot # 958786 ...

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Thank you for your reply. Both of these antibodies are tissue culture supernatant meaning that it is not possible to determine antibody concentration, since tissue culture supernatant contains proteins besides the antibody of interest. Supernat...

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Thank you for your enquiry. There's no concentration information available for this antibody as it is provided in an unpurified form (tissue culture supernatant) and we cannot determine the concentration for unpurified products. To use the antibody in ...

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Thank you for your enquiry. The concentration of the lots that we currently have in stock is 66 ug/ml. If you have any additional questions, please contact us again.

Thank you for your enquiry. We are very sorry to hear that you are having some difficulty with this product. We would like to confirm that the two batches you are having are different, however we have not received any technical enquiry which would ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"