概述

  • 产品名称Anti-TAF8抗体
    参阅全部 TAF8 一抗
  • 描述
    兔多克隆抗体to TAF8
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 109-158 (AKRSQRMVIT APPVTNQPVT PKALTAGQNR PHPPHIPSHF PEFPDPHTYI) of Mouse TAF8 (NP_071298).

  • 阳性对照
    • Mouse Heart lysate.

性能

应用

Our Abpromise guarantee covers the use of ab118730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 34 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription. Plays a role in the differentiation of preadipocyte fibroblasts to adipocytes, however, does not seem to play a role in differentiation of myoblasts. Required for the integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell mass which constitute the pluripotent cell population of the early embryo.
  • 序列相似性Belongs to the TAF8 family.
    Contains 1 histone-fold domain.
  • 结构域Ectopic expression of the histone fold domain acts as a dominant-negative mutant resulting in differentiation inhibition.
  • 细胞定位Nucleus. Cytoplasm. Localized in the cytoplasm and transported from the cytoplasm to the nucleus in some cells, possibly depending on the functional or developmental state of the cell.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ32821 antibody
    • hTAFII43 antibody
    • Protein taube nuss antibody
    • TAF(II)43 antibody
    • taf8 antibody
    • TAF8 RNA polymerase II, TATA box binding protein (TBP) associated factor, 43kDa antibody
    • TAF8_HUMAN antibody
    • TAFII-43 antibody
    • TAFII43 antibody
    • TATA box binding protein (TBP) associated factor, RNA polymerase II A 45/50kDa antibody
    • Taube nuss homolog (mouse) antibody
    • TBN antibody
    • TBP associated factor 8 antibody
    • TBP associated factor TAFII43 antibody
    • TBP associated factor, RNA polymerase II, 43 kD antibody
    • TBP-associated factor 43 kDa antibody
    • TBP-associated factor 8 antibody
    • Transcription initiation factor TFIID 43 kDa subunit antibody
    • Transcription initiation factor TFIID subunit 8 antibody
    see all

Anti-TAF8 antibody 图像

  • Anti-TAF8 antibody (ab118730) at 1 µg/ml + Mouse Heart lysate at 10 µg

    Predicted band size : 34 kDa

Anti-TAF8 antibody (ab118730)参考文献

ab118730 has not yet been referenced specifically in any publications.

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