概述

  • 产品名称Anti-TAF8抗体
    参阅全部 TAF8 一抗
  • 描述
    兔多克隆抗体to TAF8
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Cow, Dog, Pig, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan, Bat
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 260-310 of Human TAF8 (NP_612639.2).

  • 阳性对照
    • 293T whole cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab114114 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-10 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription. Plays a role in the differentiation of preadipocyte fibroblasts to adipocytes, however, does not seem to play a role in differentiation of myoblasts. Required for the integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell mass which constitute the pluripotent cell population of the early embryo.
    • 序列相似性Belongs to the TAF8 family.
      Contains 1 histone-fold domain.
    • 结构域Ectopic expression of the histone fold domain acts as a dominant-negative mutant resulting in differentiation inhibition.
    • 细胞定位Nucleus. Cytoplasm. Localized in the cytoplasm and transported from the cytoplasm to the nucleus in some cells, possibly depending on the functional or developmental state of the cell.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ32821 antibody
      • hTAFII43 antibody
      • Protein taube nuss antibody
      • TAF(II)43 antibody
      • taf8 antibody
      • TAF8 RNA polymerase II, TATA box binding protein (TBP) associated factor, 43kDa antibody
      • TAF8_HUMAN antibody
      • TAFII-43 antibody
      • TAFII43 antibody
      • TATA box binding protein (TBP) associated factor, RNA polymerase II A 45/50kDa antibody
      • Taube nuss homolog (mouse) antibody
      • TBN antibody
      • TBP associated factor 8 antibody
      • TBP associated factor TAFII43 antibody
      • TBP associated factor, RNA polymerase II, 43 kD antibody
      • TBP-associated factor 43 kDa antibody
      • TBP-associated factor 8 antibody
      • Transcription initiation factor TFIID 43 kDa subunit antibody
      • Transcription initiation factor TFIID subunit 8 antibody
      see all

    Anti-TAF8 antibody 图像

    • Detection of Human TAF8 by Western blot of Immunoprecipitate.
      TAF8 was immunoprecipitated from 293T whole cell lysate, using ab114114 at 6 µg/mg lysate (1 mg for IP, 20% of IP loaded). ab114114 was used for the subsequent WB at 1 µg/ml.
      Detection: Chemiluminescence with an exposure time of 30 seconds.

    Anti-TAF8 antibody (ab114114)参考文献

    ab114114 has not yet been referenced specifically in any publications.

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