概述

  • 产品名称Anti-TAF6抗体
    参阅全部 TAF6 一抗
  • 描述
    兔多克隆抗体to TAF6
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Gorilla
  • 免疫原

    Synthetic peptide, corresponding to a region within the amino acids 627-677 of Human TAF6, NP_005632.1

  • 阳性对照
    • Human bladder cell carcinoma, breast carcinoma, colon carcinoma, metastatic lymph node, non-small cell lung cancer, prostate carcinoma, testicular seminoma.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84720 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性TAF6 is a subunit of transcription factor IID (TFIID). Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Four isoforms have been identified but complete transcripts have been determined for only three isoforms. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
    • 细胞定位Nuclear
    • 数据库链接
    • 别名
      • TAF2E antibody
      • E 70/85kD antibody
      • TAF 6 antibody
      • TAF6 RNA polymerase II TATA box binding protein (TBP) associated factor 80 kD antibody
      • TAF6 RNA polymerase II, TATA box binding protein associated factor, 80kDa antibody
      • TAFII 70 antibody
      • TAFII80 antibody
      • TATA box binding protein (TBP) associated factor RNA polymerase II E 70/85kD antibody
      • TATA box binding protein (TBP) associated factor, RNA polymerase II, antibody
      • TBP associated factor 6 antibody
      • Transcription initiation factor TFIID 70 kDa subunit antibody
      • Transcription initiation factor TFIID subunit 6 antibody
      see all

    Anti-TAF6 antibody 图像

    • Detection of Human TAF6 by Immunohistochemistry.
      Sample: FFPE section of Human prostate carcinoma.
      Antibody: ab84720 used at a dilution of 1/250.
      Detection: DAB staining.
    • Detection of Human TAF6 by Immunohistochemistry.
      Sample: FFPE section of Human breast carcinoma.
      Antibody: ab84720 used at a dilution of 1/250.
      Detection: DAB staining.

    Anti-TAF6 antibody (ab84720)参考文献

    ab84720 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab84720.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"