Anti-BDP1抗体[2073D1a] (ab74415)
Key features and details
- Mouse monoclonal [2073D1a] to BDP1
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
概述
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产品名称
Anti-BDP1抗体[2073D1a] -
描述
小鼠单克隆抗体[2073D1a] to BDP1 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Recombinant fragment
预测可用于: Human -
免疫原
Recombinant fragment corresponding to Human BDP1 (internal sequence).
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阳性对照
- Immunised BDP1 recombinant fragment.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
ab74415 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum, and sterilised by filtration through a 0.22 µm membrane. -
克隆
单克隆 -
克隆编号
2073D1a -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab74415于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 294 kDa.
Please note that ab74415 has only been tested on the recombinant protein, not native Human samples. |
说明 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 294 kDa. Please note that ab74415 has only been tested on the recombinant protein, not native Human samples. |
靶标
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相关性
TAF3B1 is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. It localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. -
细胞定位
Nuclear -
数据库链接
- Entrez Gene: 55814 Human
- Omim: 607012 Human
- SwissProt: A6H8Y1 Human
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别名
- B double prime 1 subunit of RNA polymerase III transcription initiation factor IIIB antibody
- BDP 1 antibody
- BDP1 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (1)
ab74415 被引用在 1 文献中.
- Girotto G et al. Linkage study and exome sequencing identify a BDP1 mutation associated with hereditary hearing loss. PLoS One 8:e80323 (2013). IHC-P ; Mouse . PubMed: 24312468