概述

  • 产品名称Anti-TAF1C抗体
    参阅全部 TAF1C 一抗
  • 描述
    小鼠单克隆抗体to TAF1C
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 761-870 of Human TAF1C (NP_005670) with tag.

  • 阳性对照
    • TAF1C transfected 293T cell lysate. Partial recombinant tagged TAF1C protein.

性能

应用

Our Abpromise guarantee covers the use of ab77033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 96 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • RNA polymerase I-specific TBP-associated factor 110 kDa antibody
    • SL1 antibody
    • Taf1c antibody
    • TAF1C_HUMAN antibody
    • TAFI110 antibody
    • TAFI95 antibody
    • TATA box binding protein associated factor 1C antibody
    • TATA box-binding protein-associated factor 1C antibody
    • TATA box-binding protein-associated factor RNA polymerase I subunit C antibody
    • TBP associated factor 1C antibody
    • TBP associated factor RNA polymerase I 95 kDa antibody
    • TBP associated factor, RNA polymerase I, 110-KD antibody
    • TBP-associated factor 1C antibody
    • Transcription initiation factor SL1/TIF-IB subunit C antibody
    see all

Anti-TAF1C antibody 图像

  • Anti-TAF1C antibody (ab77033) at 1 µg/ml + Partial recombinant tagged TAF1C protein at 0.1 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

    Predicted band size : 96 kDa
    Observed band size : 42 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-TAF1C antibody (ab77033) at 1 µg/ml

    Lane 1 : TAF1C transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 96 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

Anti-TAF1C antibody (ab77033)参考文献

ab77033 has not yet been referenced specifically in any publications.

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