概述

  • 产品名称Anti-TAF1C抗体
    参阅全部 TAF1C 一抗
  • 描述
    兔多克隆抗体to TAF1C
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Guinea pig
  • 免疫原

    Synthetic peptide corresponding to a region within C-terminal amino acids 701-750 (RRHRGETSET QTQSKRPKRR TQLSSTFSSF TSYLDSPDAS SAPRSQDLST) of Mouse TAF1C (NP_067416).

  • 阳性对照
    • Mouse Uterus Lysate

性能

应用

Our Abpromise guarantee covers the use of ab108281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 95 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • RNA polymerase I-specific TBP-associated factor 110 kDa antibody
    • SL1 antibody
    • Taf1c antibody
    • TAF1C_HUMAN antibody
    • TAFI110 antibody
    • TAFI95 antibody
    • TATA box binding protein associated factor 1C antibody
    • TATA box-binding protein-associated factor 1C antibody
    • TATA box-binding protein-associated factor RNA polymerase I subunit C antibody
    • TBP associated factor 1C antibody
    • TBP associated factor RNA polymerase I 95 kDa antibody
    • TBP associated factor, RNA polymerase I, 110-KD antibody
    • TBP-associated factor 1C antibody
    • Transcription initiation factor SL1/TIF-IB subunit C antibody
    see all

Anti-TAF1C antibody 图像

  • Anti-TAF1C antibody (ab108281) at 1 µg/ml + Mouse Uterus Lysate at 10 µg

    Predicted band size : 95 kDa

Anti-TAF1C antibody (ab108281)参考文献

ab108281 has not yet been referenced specifically in any publications.

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