概述

  • 产品名称Anti-TA1抗体
    参阅全部 TA1 一抗
  • 描述
    兔多克隆抗体to TA1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human, Chimpanzee, Rhesus monkey
  • 免疫原

    Synthetic peptide corresponding to a portion of amino acids 225-250 of Human TA1

  • 阳性对照
    • Human and rat brain lysates. Human testis tissue.

性能

应用

Our Abpromise guarantee covers the use of ab72194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 36 kDa (predicted molecular weight: 39 kDa).
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 功能Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase.
  • 组织特异性Detected in low levels in discrete regions within the central nervous system and in several peripheral tissues. Moderately expressed in stomach. Low levels in amygdala, kidney, and lung, and small intestine. Trace amounts in cerebellum, dorsal root ganglia, hippocampus, hypothalamus, liver, medulla, pancreas, pituitary, pontine reticular formation, prostate, skeletal muscle and spleen.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Taar1 antibody
    • TAAR1_HUMAN antibody
    • TaR-1 antibody
    • Trace amine associated receptor 1 antibody
    • Trace amine receptor 1 antibody
    • Trace amine-associated receptor 1 antibody
    • Trar1 antibody
    see all

Anti-TA1 antibody 图像

  • All lanes : Anti-TA1 antibody (ab72194) at 2 µg/ml

    Lane 1 : Human brain lysate
    Lane 2 : Rat brain lysate


    Predicted band size : 39 kDa
    Observed band size : 36 kDa (why is the actual band size different from the predicted?)
  • ab72194 at 10µg/ml staining TA1 in human testis by Immunohistochemistry using paraffin-embedded tissue.

Anti-TA1 antibody (ab72194)参考文献

ab72194 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab72194.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"