Anti-T Cell Receptor V gamma 3抗体[536] (ab21029)


  • 产品名称Anti-T Cell Receptor V gamma 3抗体[536]
    参阅全部 T Cell Receptor V gamma 3 一抗
  • 描述
    叙利亚仓鼠单克隆抗体[536] to T Cell Receptor V gamma 3
  • 特异性ab21029 stains <1% of cells in adult thymus (AKR), splenocytes, lymph node, adult CD4-8- thymocytes and adult CD4-8-, T splenocyte. 92% of day 14 old Balb/c fetal thymus, 86% of C57BL/6 dEC (Thy-1+) and 94% of AKR dEC (Thy-1+) stain positive using this antibody.
  • 经测试应用适用于: Flow Cyt, ICC/IF, IPmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • 表位This antibody recognizes an epitope of the variable region (V gamma 3) gene product.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, 0.01M PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号536
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab21029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 1µg for 106 cells.
    IF: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution. ab21029 immunoprecipitates the TCR heterdimer with two subunits of apparent molecular mass of 52 and 42kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable) , J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Several V segments of the gamma locus are known to be incapable of encoding a protein and are considered pseudogenes. Somatic rearrangment of the gamma locus has been observed in T cells derived from patients with T cell leukemia and ataxia telangiectasia.
    • 细胞定位Membrane; Single-pass membrane protein
    • 数据库链接
    • 别名
      • T cell rearranging gene gamma antibody
      • T cell receptor gamma locus antibody
      • T-cell receptor gamma chain C region PT-gamma-1/2 antibody
      • T-cell receptor gamma-2 chain C region antibody
      • tcrg antibody
      • TCRGC2 antibody
      • trg antibody
      • TRGC2 antibody
      • TRGC2(2X) antibody
      • TRGC2(3X) antibody
      see all

    Anti-T Cell Receptor V gamma 3 antibody [536] (ab21029)参考文献

    ab21029 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting Abcam.

    I am unable to locate the rat sequence for T Cell Receptor V gamma 3, without this sequence, I am unable to say one way or the other, whether ab21209 would work on rat tissue or not. If you could please provide ...

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    Thank you for contacting Abcam and for your interest in our products.

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