Synthetic peptide conjugated to KLH, corresponding to to a region within internal sequence amino acids 242-272 of Human SYT2 (NP_796376.2, NP_001129976.1).
NCI-H292 cell line lysate.
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Preservative: 0.09% Sodium azide
Constituent: 99% PBS
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Immunogen affinity purified
ab116323 is purified through a Protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 47 kDa.
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
Belongs to the synaptotagmin family.
Contains 2 C2 domains.
The first C2 domain mediates Ca(2+)-dependent phospholipid binding.
The second C2 domain mediates interaction with Stonin 2.
Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane. Synaptic vesicles and chromaffin granules.
Information by UniProt
Synaptotagmin 2 antibody
Synaptotagmin II antibody
has not yet been referenced specifically in any publications.
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