Anti-Syntrophin gamma 2抗体(ab15713)

概述

  • 产品名称Anti-Syntrophin gamma 2抗体
    参阅全部 Syntrophin gamma 2 一抗
  • 描述
    山羊多克隆抗体to Syntrophin gamma 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide: DSQSLARKYMYSS, corresponding to C terminal amino acids 527-539 of Syntrophin gamma 2.

  • 阳性对照
    • Human duodenum and ileum lysate. Preliminary experiments gave ~28kDa and 20kDa bands in Human brain and human testis lysates

性能

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应用

Our Abpromise guarantee covers the use of ab15713 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 3 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 62 kDa).Can be blocked with Human Syntrophin gamma 2 peptide (ab23267).

靶标

  • 功能Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
  • 组织特异性Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia.
  • 序列相似性Belongs to the syntrophin family.
    Contains 1 PDZ (DHR) domain.
    Contains 1 PH domain.
  • 结构域The association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane.
  • 细胞定位Cell membrane > sarcolemma. Cytoplasm > cytoskeleton. In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 9530013L23 antibody
    • G2SYN antibody
    • Gamma-2-syntrophin antibody
    • Gamma2-syntrophin antibody
    • SNTG2 antibody
    • SNTG2_HUMAN antibody
    • SYN5 antibody
    • Syntrophin 5 antibody
    • Syntrophin-5 antibody
    see all

Anti-Syntrophin gamma 2 antibody 图像

  • Anti-Syntrophin gamma 2 antibody (ab15713) at 3 µg/ml + lysate prepared from human duodenum tissue, in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 62 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 110 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 1 hour

Anti-Syntrophin gamma 2 antibody (ab15713)参考文献

ab15713 has not yet been referenced specifically in any publications.

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