Anti-Syntaxin-binding protein 4抗体(ab118123)

概述

  • 产品名称Anti-Syntaxin-binding protein 4抗体
    参阅全部 Syntaxin-binding protein 4 一抗
  • 描述
    小鼠单克隆抗体to Syntaxin-binding protein 4
  • 经测试应用适用于: WB, ELISA, Sandwich ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-245 of Human Syntaxin-binding protein 4 with proprietary tag (AAH41485).

性能

应用

Our Abpromise guarantee covers the use of ab118123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 62 kDa. This antibody has only been tested in WB against the recombinant protein used as immunogen. We have no data on the detection of endogenous protein.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

靶标

  • 功能Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
  • 序列相似性Contains 1 PDZ (DHR) domain.
    Contains 1 WW domain.
  • 翻译后修饰Phosphorylated on Ser-99 by PKB/AKT2 after insulin treatment. Phosphorylation on Ser-99 abolishes the interaction with STX4A (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ16496 antibody
    • MGC149829 antibody
    • MGC50337 antibody
    • OTTHUMP00000082667 antibody
    • OTTHUMP00000227400 antibody
    • STX4-interacting protein antibody
    • STXB4_HUMAN antibody
    • Stxbp4 antibody
    • Synip antibody
    • Syntaxin 4 interacting protein antibody
    • Syntaxin 4-interacting protein antibody
    • Syntaxin binding protein 4 antibody
    • Syntaxin-binding protein 4 antibody
    see all

Anti-Syntaxin-binding protein 4 antibody 图像

  • Anti-Syntaxin-binding protein 4 antibody (ab118123) at 5 µg/ml + recombinant immunogen at 0.2 µg

    Predicted band size : 62 kDa
  • Detection limit for recombinant tagged Syntaxin-binding protein 4 is 0.1 ng/ml as a capture antibody.

Anti-Syntaxin-binding protein 4 antibody (ab118123)参考文献

ab118123 has not yet been referenced specifically in any publications.

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