RabMAb

Anti-Syntaxin 1a抗体[SP36], prediluted (ab73915)

概述

  • 产品名称Anti-Syntaxin 1a抗体[SP36], prediluted
    参阅全部 Syntaxin 1a 一抗
  • 描述
    兔单克隆抗体[SP36] to Syntaxin 1a, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to the N terminus of human Syntaxin 1a

  • 表位N terminus
  • 阳性对照
    • Human brain tissue

性能

应用

Our Abpromise guarantee covers the use of ab73915 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready to use for 30 minutes at room temperature.
    Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at room temperature for 20 minutes.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
    • 组织特异性Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.
    • 疾病相关Note=STX1A is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
    • 序列相似性Belongs to the syntaxin family.
      Contains 1 t-SNARE coiled-coil homology domain.
    • 细胞定位Secreted and Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome.
    • Information by UniProt
    • 数据库链接
    • 别名
      • HPC 1 antibody
      • Neuron specific antigen HPC1 antibody
      • Neuron-specific antigen HPC-1 antibody
      • OTTHUMP00000174615 antibody
      • OTTHUMP00000174616 antibody
      • OTTHUMP00000174617 antibody
      • OTTHUMP00000174618 antibody
      • P35-1 antibody
      • STX1 antibody
      • STX1A antibody
      • STX1A_HUMAN antibody
      • SYN1A antibody
      • Syntaxin 1A (brain) antibody
      • Syntaxin 1A brain antibody
      • Syntaxin-1A antibody
      see all

    Anti-Syntaxin 1a antibody [SP36], prediluted 图像

    • ab73915, ready to use, staining Syntaxin 1a in formalin fixed, paraffin embedded human brain tissue by Immunohistochemistry.

    Anti-Syntaxin 1a antibody [SP36], prediluted (ab73915)参考文献

    ab73915 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Sample Human Tissue sections (brain, pediatric)
    Specification brain, pediatric
    Fixative Formaldehyde
    Antigen retrieval step Heat mediated - Buffer/Enzyme Used: citrate pH6, 100C 20 minutes
    Permeabilization No
    Username

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    提交于 Dec 15 2009

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"