概述

  • 产品名称Anti-Syntaxin 13抗体[4E212]
    参阅全部 Syntaxin 13 一抗
  • 描述
    小鼠单克隆抗体[4E212] to Syntaxin 13
  • 特异性ab18011 identifies recombinant rat syntaxin 13 as an ~38kD protein (corresponding to the predicted band). Additional bands of 27 and 37kD may also be recognized and are believed to correspond to degradation products of syntaxin 13.
  • 经测试应用适用于: WBmore details
    不适用于: ICC/IF
  • 种属反应性
    与反应: Mouse, Rat, Hamster, Dog
  • 免疫原

    Recombinant fragment (Rat Syntaxin 13 cytoplasmic domain).

  • 阳性对照
    • Rat or mouse brain extract.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 50% Glycerol, PBS, 0.1mM PMSF
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号4E212
  • 骨髓瘤NS1
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab18011 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa.
  • 应用说明Is unsuitable for ICC/IF.
  • 靶标

    • 相关性Syntaxin 13 is an integral membrane protein that belongs to the t-SNARE family, a group of proteins involved in protein transport. Confocal immunofluoresence and electron microscopy studies have shown that syntaxin 13 is primarily localized to tubular early and recycling endosomes, where it colocalizes with transferrin receptor, and it is also localized in endosomal vacuoles. Syntaxin 13 has been found to be expressed in all tissues, with higher levels of the protein found in brain, lung, spleen, thymus and testes. Immunoprecipitation studies show that syntaxin 13 complexes with beta-SNAP, VAMP2/3, and SNAP25. The binding of this complex to alpha-SNAP and NSF is terminated in the presence of ATP. These results suggest that syntaxin 13 is a SNARE protein which mediates the recycling protein flow through tubulo vesicular recycling endosomes.
    • 细胞定位Tubular early and recycling endosomes and endosomal vacuoles.
    • 别名
      • Dm Syx13 antibody
      • ff16 antibody
      • Syntaxin13 antibody
      • Syx13 antibody

    Anti-Syntaxin 13 antibody [4E212] (ab18011)参考文献

    This product has been referenced in:
    • Chung WY  et al. WNK4 inhibits plasma membrane targeting of NCC through regulation of syntaxin13 SNARE formation. Cell Signal 25:2469-77 (2013). Read more (PubMed: 23993962) »

    See 1 Publication for this product

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