概述

  • 产品名称Anti-Syntaxin 13抗体[15G2]
    参阅全部 Syntaxin 13 一抗
  • 描述
    小鼠单克隆抗体[15G2] to Syntaxin 13
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Hamster, Dog
  • 免疫原

    Recombinant full length protein (Rat).

  • 阳性对照
    • Rat or Mouse Brain Tissue Extract.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号15G2
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab13261 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 38 kDa. Additional bands of 27 and 37 kDa may also be recognized, and are believed to correspond to degradation products of syntaxin 13.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Syntaxin 13 is an integral membrane protein that belongs to the t-SNARE family, a group of proteins involved in protein transport. Confocal immunofluoresence and electron microscopy studies have shown that syntaxin 13 is primarily localized to tubular early and recycling endosomes, where it colocalizes with transferrin receptor, and it is also localized in endosomal vacuoles. Syntaxin 13 has been found to be expressed in all tissues, with higher levels of the protein found in brain, lung, spleen, thymus and testes. Immunoprecipitation studies show that syntaxin 13 complexes with beta-SNAP, VAMP2/3, and SNAP25. The binding of this complex to alpha-SNAP and NSF is terminated in the presence of ATP. These results suggest that syntaxin 13 is a SNARE protein which mediates the recycling protein flow through tubulo vesicular recycling endosomes.
    • 细胞定位Tubular early and recycling endosomes and endosomal vacuoles.
    • 别名
      • Dm Syx13 antibody
      • ff16 antibody
      • Syntaxin13 antibody
      • Syx13 antibody

    Anti-Syntaxin 13 antibody [15G2] (ab13261)参考文献

    This product has been referenced in:
    • Suh YH  et al. Deletion of SNAP-23 Results in Pre-Implantation Embryonic Lethality in Mice. PLoS One 6:e18444 (2011). WB ; Mouse . Read more (PubMed: 21479242) »
    • Sobota JA  et al. Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory-pathway proteins. J Cell Sci 122:3542-53 (2009). WB ; Mouse . Read more (PubMed: 19737820) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab13261.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"