概述

  • 产品名称Anti-Syndecan 4抗体
    参阅全部 Syndecan 4 一抗
  • 描述
    兔多克隆抗体to Syndecan 4
  • 特异性ab74139 detects endogenous levels of total Syndecan 4 protein.
  • 经测试应用适用于: WB, ELISA, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic non-phosphopeptide from human Syndecan 4 around the phosphorylation site of serine 179 (E-G-SP-Y-D).

  • 阳性对照
    • Human brain tissue. Extracts from HepG2 cells. HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab74139 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
ELISA 1/10000.
IHC-P 1/50 - 1/100.
ICC/IF 1/500 - 1/1000.

靶标

  • 功能Cell surface proteoglycan that bears heparan sulfate.
  • 组织特异性Expressed in epithelial and fibroblastic cells.
  • 序列相似性Belongs to the syndecan proteoglycan family.
  • 翻译后修饰Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
  • 细胞定位Membrane. Secreted. Shedding of the ectodomain produces a soluble form.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Amphiglycan antibody
    • MGC22217 antibody
    • OTTHUMP00000031788 antibody
    • ryudocan amphiglycan antibody
    • Ryudocan antibody
    • Ryudocan core protein antibody
    • SDC 4 antibody
    • Sdc4 antibody
    • SDC4_HUMAN antibody
    • SYND 4 antibody
    • SYND4 antibody
    • syndecan 4 antibody
    • syndecan 4 (amphiglycan, ryudocan) antibody
    • syndecan proteoglycan 4 antibody
    • Syndecan-4 antibody
    • Syndecan4 antibody
    see all

Anti-Syndecan 4 antibody 图像

  • Immunohistochemistry analysis of human brain tissue using ab74139, at 1/50 dilution, in the presence (right panel) or absence (left panel) of immunising peptide.
  • All lanes : Anti-Syndecan 4 antibody (ab74139) at 1/500 dilution

    Lane 1 : Extracts from HepG2 cells
    Lane 2 : Extracts from HepG2 cells with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 22 kDa
    Observed band size : 22 kDa
  • Immunofluorescence analysis of HeLa cells using ab74139, at 1/500 dilution, in the presence (right panel) or absence (left panel) of immunising peptide.

Anti-Syndecan 4 antibody (ab74139)参考文献

ab74139 has not yet been referenced specifically in any publications.

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