The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.05 - 2 µg/ml. Detects a band of approximately 15 kDa (predicted molecular weight: 15 kDa).
功能Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues.
翻译后修饰Contains intrachain disulfide bonds.
细胞定位Cytoplasmic vesicle > secretory vesicle membrane. Localizes to zymogen granules (By similarity). Associated with lipid rafts in a cholesterol-dependent manner.