Anti-Synaptopodin抗体(ab117702)

概述

  • 产品名称
    Anti-Synaptopodin抗体
    参阅全部 Synaptopodin 一抗
  • 描述
    兔多克隆抗体to Synaptopodin
  • 经测试应用
    适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide from the C terminal region of Human Synaptopodin, conjugated to KLH.

  • 阳性对照
    • Human perineural or perivascular process.

性能

应用

Our Abpromise guarantee covers the use of ab117702 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 99 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能
    Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.
  • 组织特异性
    Expressed in cerebral cortex.
  • 序列相似性
    Belongs to the synaptopodin family.
  • 翻译后修饰
    O-glycosylated.
    Isoform 2 is phosphorylated on Ser-826, Thr-836, Ser-840 and Ser-871.
  • 细胞定位
    Cytoplasm > cytoskeleton. Cell junction > tight junction. Perikaryon. Cell projection > dendritic spine. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Asssociated with dendritic spines of a subset of synapses.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA1029 antibody
    • Synaptopodin antibody
    • SYNPO antibody
    • SYNPO_HUMAN antibody

图片

  • Human Perineural Processes, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117702 at 5µg/ml.
  • Human Perivascular Processes, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117702 at 5µg/ml.

文献

ab117702 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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