Anti-Synaptopodin抗体(ab117702)

概述

  • 产品名称Anti-Synaptopodin抗体
    参阅全部 Synaptopodin 一抗
  • 描述
    兔多克隆抗体to Synaptopodin
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide from the C terminal region of Human Synaptopodin, conjugated to KLH.

  • 阳性对照
    • Human perineural or perivascular process.

性能

应用

Our Abpromise guarantee covers the use of ab117702 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 99 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.
  • 组织特异性Expressed in cerebral cortex.
  • 序列相似性Belongs to the synaptopodin family.
  • 翻译后修饰O-glycosylated.
    Isoform 2 is phosphorylated on Ser-826, Thr-836, Ser-840 and Ser-871.
  • 细胞定位Cytoplasm > cytoskeleton. Cell junction > tight junction. Perikaryon. Cell projection > dendritic spine. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Asssociated with dendritic spines of a subset of synapses.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA1029 antibody
    • Synaptopodin antibody
    • SYNPO antibody
    • SYNPO_HUMAN antibody

Anti-Synaptopodin antibody 图像

  • Human Perineural Processes, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117702 at 5µg/ml.
  • Human Perivascular Processes, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117702 at 5µg/ml.

Anti-Synaptopodin antibody (ab117702)参考文献

ab117702 has not yet been referenced specifically in any publications.

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