概述

  • 产品名称Anti-Synaptopodin 2抗体
    参阅全部 Synaptopodin 2 一抗
  • 描述
    兔多克隆抗体to Synaptopodin 2
  • 经测试应用适用于: WB, IHC-Frmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Synthetic peptide:

    QQNGFSGTSETANIQRMVPM

    conjugated to KLH, corresponding to amino acids 566-585 in the mid region of Human Synaptopodin 2. This sequence is not found in human or rat synaptopodin.

  • 阳性对照
    • WB: A cytosolic fraction of rat skeletal muscle. IHC-Fr: rat skeletal muscle and rat kidney.

性能

应用

Our Abpromise guarantee covers the use of ab50192 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 118 kDa. Additional lower bands may be observed which may represent degradation products. The staining can be blocked by the immunizing peptide.
IHC-Fr Use a concentration of 1 - 2 µg/ml.

靶标

  • 功能Has an actin-binding and actin-bundling activity.
  • 组织特异性Skeletal muscle-specific.
  • 序列相似性Belongs to the synaptopodin family.
    Contains 1 PDZ (DHR) domain.
  • 细胞定位Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm in a differentiation-dependent and stress-induced fashion. Localizes to the Z-disk in mature striated muscle. The nuclear export is XPO1-dependent (By similarity). Localized in a fiber-like pattern. partly overlapping with filamentous actin.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp686G051 antibody
    • Genethonin 2 antibody
    • Genethonin-2 antibody
    • Myopodin antibody
    • striated muscle specific antibody
    • Synaptopodin-2 antibody
    • SYNP2_HUMAN antibody
    • SYNPO 2 antibody
    • Synpo2 antibody
    see all

Anti-Synaptopodin 2 antibody (ab50192)参考文献

This product has been referenced in:
  • Kai F  et al. Myopodin isoforms alter the chemokinetic response of PC3 cells in response to different migration stimuli via differential effects on Rho-ROCK signaling pathways. Carcinogenesis 33:2100-7 (2012). Read more (PubMed: 22915763) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"