RabMAb

Anti-Synaptophysin抗体[SP11], prediluted (ab27601)

概述

  • 产品名称Anti-Synaptophysin抗体[SP11], prediluted
    参阅全部 Synaptophysin 一抗
  • 描述
    兔单克隆抗体[SP11] to Synaptophysin, prediluted
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide of human Synaptophysin.

  • 表位Ab27601 recognises an epitope on the C terminus human Synaptophysin.
  • 阳性对照
    • Pancreas, Pheochromocytoma and Human neuroendocrine tumor.

性能

应用

Our Abpromise guarantee covers the use of ab27601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use at an assay dependent concentration.

靶标

  • 功能Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
  • 组织特异性Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
  • 疾病相关Mental retardation, X-linked, SYP-related
  • 序列相似性Belongs to the synaptophysin/synaptobrevin family.
    Contains 1 MARVEL domain.
  • 结构域The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.
  • 翻译后修饰Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
  • 细胞定位Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell junction, synapse, synaptosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Major synaptic vesicle protein p38 antibody
    • MRX96 antibody
    • MRXSYP antibody
    • Syn p38 antibody
    • Synaptophysin antibody
    • Syp antibody
    • SYPH antibody
    • SYPH_HUMAN antibody
    • SypI antibody
    see all

Anti-Synaptophysin antibody [SP11], prediluted 图像

  • Ab27601, prediluted, staining Synaptophysin in formalin fixed paraffin embedded human neuroendocrine tumor sections by Immunohistochemistry.
  • Anti-Synaptophysin antibody [SP11], prediluted (ab27601) + lysate prepared from brain

Anti-Synaptophysin antibody [SP11], prediluted (ab27601)参考文献

ab27601 has not yet been referenced specifically in any publications.

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