RabMAb

Anti-Synaptophysin抗体[SP11] (ab16659)

概述

  • 产品名称Anti-Synaptophysin抗体[SP11]
    参阅全部 Synaptophysin 一抗
  • 描述
    兔单克隆抗体[SP11] to Synaptophysin
  • 经测试应用适用于: WB, IHC-P, IHC-FoFrmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human).

  • 表位C-terminus
  • 阳性对照
    • Pancreas or Pheochromocytoma

性能

应用

Our Abpromise guarantee covers the use of ab16659 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/200. Predicted molecular weight: 38 kDa.
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
IHC-FoFr Use at an assay dependent concentration.

靶标

  • 功能Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
  • 组织特异性Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
  • 疾病相关Mental retardation, X-linked, SYP-related
  • 序列相似性Belongs to the synaptophysin/synaptobrevin family.
    Contains 1 MARVEL domain.
  • 结构域The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.
  • 翻译后修饰Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
  • 细胞定位Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell junction, synapse, synaptosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Major synaptic vesicle protein p38 antibody
    • MRX96 antibody
    • MRXSYP antibody
    • Syn p38 antibody
    • Synaptophysin antibody
    • Syp antibody
    • SYPH antibody
    • SYPH_HUMAN antibody
    • SypI antibody
    see all

Anti-Synaptophysin antibody [SP11] 图像

  • Immunohistochemical staining of human neuroendocrine tumor with ab16659.

  • Immunohistochemical staining of human pancreas with ab16659.

  • Anti-Synaptophysin antibody [SP11] (ab16659) + lysate prepared from brain

    Predicted band size : 38 kDa

Anti-Synaptophysin antibody [SP11] (ab16659)参考文献

This product has been referenced in:

See 1 Publication for this product

Product Wall

Thank you for your enquiry. We don't have a blocking peptide for this antibody within our product range. Best of luck with your research.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"