Anti-Synaptobrevin抗体[4E240] (ab18013)

概述

  • 产品名称Anti-Synaptobrevin抗体[4E240]
    参阅全部 Synaptobrevin 一抗
  • 描述
    小鼠单克隆抗体[4E240] to Synaptobrevin
  • 特异性Detects a ~18kD protein in WB, corresponding to predicted size of VAMP from human, mouse, rat, bovine, guinea pig, hamster, monkey, porcine, rabbit, sheep and Xenopus tissue. This antibody detects VAMP1 (amino acids 1-118) and VAMP2 (amino acids 33-96)-GST fusion proteins expressed in E. coli. No reactivity was seen with a ~18kD protein in mouse liver extracts.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Sheep, Rabbit, Guinea pig, Hamster, Cow, Human, Pig, Xenopus laevis, Monkey
  • 免疫原

    Tissue/ cell preparation (Human). Mice were immunized with synaptic vesicle containing fractions which were immunoprecipitated from human brain homogenates using anti-human synaptophysin monoclonal antibodies.

  • 阳性对照
    • Rat brain.

性能

应用

Our Abpromise guarantee covers the use of ab18013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 13 kDa.

靶标

  • 相关性Synaptobrevins are highly conserved between vertebrates and invertebrates. It is a major constituent of synaptic vesicles and peptidergic secretory granules in all neurons examined so far. In addition, it is present on secretory granules of neuroendocrine cells. Synaptobrevins, Syntaxins, and the 25 kDa synaptosomal associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane.
  • 细胞定位Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane. Single-pass type IV membrane protein. Cell junction > synapse > synaptosome. Isoform 3 is found in mitochondria, mitochondrial outer membrane.
  • 数据库链接
  • 别名
    • SYB antibody
    • SYB1 antibody
    • Synaptobrevin 1 antibody
    • VAMP antibody
    • VAMP1 antibody
    • Vesicle associated membrane protein 1 antibody
    see all

Anti-Synaptobrevin antibody [4E240] (ab18013)参考文献

ab18013 has not yet been referenced specifically in any publications.

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