Anti-Synapsin I (phospho S603)抗体(ab13879)

概述

  • 产品名称Anti-Synapsin I (phospho S603)抗体
    参阅全部 Synapsin I 一抗
  • 描述
    兔多克隆抗体to Synapsin I (phospho S603)
  • 特异性The antibody is specific for Synapsin I phosphorylated at Ser603.
  • 经测试应用适用于: Dot blot, WBmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    This antibody was developed against synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho-Ser603 of rat Synapsin I.

  • 常规说明Aliquots may be taken without freeze/thawing due to the presence of 50% glycerol.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 100µg/ml BSA, 150mM Sodium Chloride, 10mM HEPES. pH 7.5
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明The antibody was purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab13879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Dot blot 1/1000.
WB 1/1000. Predicted molecular weight: 84.6 kDa.

靶标

  • 功能Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
  • 疾病相关Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
  • 序列相似性Belongs to the synapsin family.
  • 翻译后修饰Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cell junction > synapse. Golgi apparatus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Brain protein 4.1 antibody
    • SYN 1 antibody
    • SYN 1a antibody
    • SYN 1b antibody
    • SYN I antibody
    • SYN1 antibody
    • SYN1_HUMAN antibody
    • SYN1a antibody
    • SYN1b antibody
    • Synapsin 1 antibody
    • Synapsin I antibody
    • Synapsin-1 antibody
    • Synapsin1 antibody
    • SynapsinI antibody
    • SYNI antibody
    see all

Anti-Synapsin I (phospho S603) antibody 图像



  • Predicted band size : 84.6 kDa


    Right lane-ab13879 at 1/1000 dilution detecting synapsin I by Western blot. Left lane-Peptide block.

Anti-Synapsin I (phospho S603) antibody (ab13879)参考文献

ab13879 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. I can confirm that the immunogen for this product is phospho-Ser603 of rat Synapsin I. I sincerely apologize that we had a typing error on the datasheet and rest assured that it has now been corrected. Thank you agai...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"