概述

  • 产品名称Anti-Synapsin I抗体
    参阅全部 Synapsin I 一抗
  • 描述
    兔多克隆抗体to Synapsin I
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Cow, Human
    预测可用于: Dog, Pig
  • 免疫原

    Synthetic peptide:

    GGQQRQGPPQKPPGPAGP

    conjugated to KLH, corresponding to amino acids 583-600 of Human Synapsin I (GenBank accession number: M58378).

  • 阳性对照
    • Rar brain tissue extract

性能

应用

Our Abpromise guarantee covers the use of ab90501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.05 µg/ml. Predicted molecular weight: 74 kDa.
IP Use a concentration of 10 µg/ml.

靶标

  • 功能Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
  • 疾病相关Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
  • 序列相似性Belongs to the synapsin family.
  • 翻译后修饰Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cell junction > synapse. Golgi apparatus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Brain protein 4.1 antibody
    • SYN 1 antibody
    • SYN 1a antibody
    • SYN 1b antibody
    • SYN I antibody
    • SYN1 antibody
    • SYN1_HUMAN antibody
    • SYN1a antibody
    • SYN1b antibody
    • Synapsin 1 antibody
    • Synapsin I antibody
    • Synapsin-1 antibody
    • Synapsin1 antibody
    • SynapsinI antibody
    • SYNI antibody
    see all

Anti-Synapsin I antibody (ab90501)参考文献

ab90501 has not yet been referenced specifically in any publications.

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