概述

  • 产品名称
    Anti-Synapsin I抗体
    参阅全部 Synapsin I 一抗
  • 描述
    兔多克隆抗体to Synapsin I
  • 经测试应用
    适用于: WB, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Cow, Human
    预测可用于: Dog, Pig
  • 免疫原

    Synthetic peptide:

    GGQQRQGPPQKPPGPAGP

    conjugated to KLH, corresponding to amino acids 583-600 of Human Synapsin I (GenBank accession number: M58378).

  • 阳性对照
    • Rar brain tissue extract

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 75mM Sodium chloride, 5mM EDTA, 25mM Sodium borate, 100mM Boric Acid, pH 8.4
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    This antibody was purified on a peptide bound immunoaffinity column.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab90501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.05 µg/ml. Predicted molecular weight: 74 kDa.
IP Use a concentration of 10 µg/ml.

靶标

  • 功能
    Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
  • 疾病相关
    Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
  • 序列相似性
    Belongs to the synapsin family.
  • 翻译后修饰
    Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Cell junction > synapse. Golgi apparatus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Brain protein 4.1 antibody
    • SYN 1 antibody
    • SYN 1a antibody
    • SYN 1b antibody
    • SYN I antibody
    • SYN1 antibody
    • SYN1_HUMAN antibody
    • SYN1a antibody
    • SYN1b antibody
    • Synapsin 1 antibody
    • Synapsin I antibody
    • Synapsin-1 antibody
    • Synapsin1 antibody
    • SynapsinI antibody
    • SYNI antibody
    see all

文献

ab90501 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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