Anti-Synapsin I抗体(ab57467)

概述

  • 产品名称Anti-Synapsin I抗体
    参阅全部 Synapsin I 一抗
  • 描述
    小鼠单克隆抗体to Synapsin I
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: EIFGGLDICA VEALHGKDGR DHIIEVVGSS MPLIGDHQDE DKQLIVELVV NKMAQALPRQ RQRDASPGRG SHGQTPSPGA LPLGRQTSQ, corresponding to amino acids 362-451 of Human Synapsin I

性能

应用

Our Abpromise guarantee covers the use of ab57467 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
    • 疾病相关Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
    • 序列相似性Belongs to the synapsin family.
    • 翻译后修饰Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Cell junction > synapse. Golgi apparatus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Brain protein 4.1 antibody
      • SYN 1 antibody
      • SYN 1a antibody
      • SYN 1b antibody
      • SYN I antibody
      • SYN1 antibody
      • SYN1_HUMAN antibody
      • SYN1a antibody
      • SYN1b antibody
      • Synapsin 1 antibody
      • Synapsin I antibody
      • Synapsin-1 antibody
      • Synapsin1 antibody
      • SynapsinI antibody
      • SYNI antibody
      see all

    Anti-Synapsin I antibody 图像



    • Predicted band size : 70 kDa
      Synapsin I antibody (ab57467) at 1ug/lane + MCF-7 cell lysate at 25ug/lane.

    Anti-Synapsin I antibody (ab57467)参考文献

    ab57467 has not yet been referenced specifically in any publications.

    Product Wall

    Application Immunocytochemistry/ Immunofluorescence
    Sample Human Cell (Poor)
    Permeabilization Yes - 0.2% Triton-X-100
    Specification Poor
    Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 10µg/mL · Temperature: 25°C
    Fixative Formaldehyde
    Username

    Dr. Amy Zhu

    Verified customer

    提交于 May 20 2016

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"