概述

  • 产品名称Anti-Symplekin抗体
    参阅全部 Symplekin 一抗
  • 描述
    兔多克隆抗体to Symplekin
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 1224-1274 of Human Symplekin (NP_004810.2).

  • 阳性对照
    • Anaplastic Thyroid Carcinoma, Breast Carcinoma, Colon Carcinoma, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Skin Basal Cell Carcinoma, Stomach Adenocarcinoma, Testicular Seminoma.

性能

应用

Our Abpromise guarantee covers the use of ab99257 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Antigen retrieval is recommended. Antigen retrieval with citrate buffer will enhance staining. Likely to work with frozen sections

靶标

  • 相关性Symplekin (SYMPK) can associate with tight junctions, functions in the regulation of polyadenylation and promotes gene expression. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation.
  • 细胞定位Cytoplasm, cytoskeleton. Cell junction, tight junction; Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction; Cytoplasmic side. Nucleus, nucleoplasm. Note Cytoplasmic face of adhesion plaques (major) and nucleoplasm (minor) (in cells with TJ). Nucleoplasm (in cells without TJ). Nuclear bodies of heat-stressed cells.
  • 数据库链接
  • 别名
    • FLJ27092 antibody
    • SPK antibody
    • SYM antibody
    • SYMPK antibody

Anti-Symplekin antibody 图像

  • ab99257 at 1/250 dilution staining Symplekin in formalin-fixed, paraffin-embedded section of Human colon carcinoma by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised DAB.
  • ab99257 at 1/250 dilution staining Symplekin in formalin-fixed, paraffin-embedded section of Human Seminoma by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised DAB.
  • ab99257 at 1/250 dilution staining Symplekin in formalin-fixed, paraffin-embedded section of Human pancreatic islet cell tumor by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised DAB.

Anti-Symplekin antibody (ab99257)参考文献

ab99257 has not yet been referenced specifically in any publications.

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