概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-LKHHSENKGLDKV
    • 氨基酸113 to 125

技术指标

Our Abpromise guarantee covers the use of ab45744 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • FLJ53045
    • FLJ53762
    • FLJ54296
    • HGNC:11486
    • OTTHUMP00000024258
    • OTTHUMP00000024259
    • OTTHUMP00000225953
    • SYBL 1
    • SYBL1
    • Synaptobrevin like 1
    • Synaptobrevin-like protein 1
    • Tetanus insensitive VAMP
    • Tetanus neurotoxin insensitive VAMP
    • Tetanus-insensitive VAMP
    • TI VAMP
    • Ti-VAMP
    • TIVAMP
    • VAMP-7
    • VAMP7
    • VAMP7_HUMAN
    • Vesicle-associated membrane protein 7
    see all
  • 功能Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.
  • 组织特异性Detected in all tissues tested.
  • 序列相似性Belongs to the synaptobrevin family.
    Contains 1 longin domain.
    Contains 1 v-SNARE coiled-coil homology domain.
  • 细胞定位Cytoplasmic vesicle > secretory vesicle membrane. Golgi apparatus > trans-Golgi network membrane. Late endosome membrane. Lysosome membrane. Endoplasmic reticulum membrane. Cytoplasmic vesicle > phagosome membrane.
  • Information by UniProt

SYBL1 peptide (113-125) (ab45744)参考文献

ab45744 has not yet been referenced specifically in any publications.

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